Mbz, as with the other benzimidazoles, binds to the colchicine-binding domain of tubulin 26 .
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if you are taking colchicine to treat a painful attack of gouty arthritis and you experience nausea, vomiting, or diarrhea, stop taking colchicine , even if pain continues, unless your doctor directs otherwise.
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our finding that minimal telomere clustering appeared in colchicine-treated nuclei, as shown by the formation of telomere miniclusters and by the shift to smaller nearest neighbor distances fig.
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