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– methotrexate a drug used for suppressing the immune system, and often.
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all patients received stable doses of methotrexate and daily calcium and vitamin d.
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teriflunomide major teriflunomide is an inhibitor of the hepatic uptake transporter organic anion transporting polypeptide oatp1b1 and the renal uptake organic anion transporter oat3, while methotrexate is a substrate of both of these transporters.
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