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11 May

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See dosage and administration ; clinical pharmacology caution should be used to ensure that the correct dose of januvia is prescribed for patients with moderate creatinine clearance 30 to 50 ml min or severe creatinine clearance 30 ml min renal impairment.

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of the total number of subjects n 3884 in pre-approval clinical safety and efficacy studies of januvia, 725 patients were 65 years and over, while 61 patients were 75 years and over.

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the national institutes of health says that januvia, or sitagliptin, stimulates insulin secretion when high blood sugar is present and inhibits glucagon secretion.

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januvia should not be used to treat patients with .

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it should not be used for the treatment of type 1 diabetes, or diabetic ketoacidosis, as januvia would have no effect for these conditions.


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