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Interestingly, in our models, the inhibition of authophagy by 3ma was found to result in the accumulation of z in autophagosome-like structures, but this was not observed for s and serpina2 variants.

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western blotting of the extracellular protein fraction isolated from skeletal muscle showed abundant serpina3n levels in tg compared with ntg mice fig.

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for example, such assays may comprise, as the adsorbent, binding moiety, or capture reagent, an antibody to one or more of the biomarkers such as serpina-1 polypeptides and or albumin polypeptides.

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immunocytochemistry of serpina3n with different organelle vesicular trafficking markers showed that serpina3n co-localized with er protein disulfide isomerase and both cis – gm130 and trans -golgi golgin 97 networks supplementary material, fig.

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