It is also contraindicated in individuals with ketonuria, serious hepatic and renal disorders, serious cardiovascular problems, serious respiratory problems, suprarenal insufficiency, chronic alcoholism, serious dystrophic illness, acute hemorrhaging, gangrene, diabetes with previous episodes of lactic acidosis or hypersensitivity to metformin.
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if you need to have any type of x-ray or ct scan using a dye that is injected into a vein, you may need to temporarily stop taking metformin.
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these drugs include thiazides and other diuretics corticosteroids phenothiazines thyroid medications estrogens birth control pills phenytoin dilantin nicotinic acid sympathomimetics calcium channel blockers ccbs isoniazid nydrazid cimetidine tagamet , by decreasing the elimination of metformin from the body, can increase the amount of metformin in the blood by 40 .
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